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Cancer patients endure extreme suffering, both mentally and physically.

Suffering lasts from the beginning of being diagnosed through the toxicity of the treatment.

Surgery, Chemo & radiation fail for many patients. Treatment is often worse than the cure!

Current State of the Art Radiation Treatments

  • Image Guided Radiation Therapy
  • Cyber-Knife
  • Gamma-Knife
  • Proton Therapy

These radiation treatments are all good for early stages with small to medium size tumors. However, these treatments were never designed to deal with large sized, late stage, and reoccurring tumors.

These Patients are dealing with the following:

  • A Painful Death Sentence
  • Tremendous Amount of Suffering
  • Palliative Care / Hospice
  • Quality of Life Concerns

ALL HOPE IS GONE

Current Conventional Practice

Current Radiation Therapy (RT) Kills EVERYTHING…the cancer/tumor, and the good immunity agents. Thus leaving the patients defenseless and creating an immunosuppressive environment.

Conceptual SFRT

NEW HOPE FOR PATIENTS

Spatial Fractional Radiation Treatment (SFRT)

Pre-Clinical Animal Studies Have Shown with Single Dose of RT:

  • Much lower toxicity
  • Good tumor control
  • Employs patients own immunity to fight the tumor/ cancer.

Pre-Clinical SFRT Data

  • The tissue sparing MRT radiation is tumor controlling.
  • This is illustrated by the brain tumor mouse survival curve plot to the left.

Clinical Data

As a reminder that for these patients’ Conventional RT did not work and that these are large, late stage and/or reoccurring. However, this is an example of using SFRT in conjunction with a conventional treatment being successful!

Clinical data graph
J Radiat Oncol 2, 103–106 (2013)

Observed Effects

of Radiation on the Human Body

Cellular Level

“Bystander Effect”

After high dose, many of the other cells around die.

Tissue Level

Summary of Vascular Changes
  • Impaired blood flow and vascular reactivity.
  • Reduced vessel density.
  • Constriction of Capillaries via amyloid deposits.
  • Capillary blockage via neutrophils.
  • Blood brain barrier leakage.
  • String Vessel formation.
  • Aberrant Angiogenes.
  • Tissue Attrophy

Immune Response Level

“Abscopal Effect”

The abscopal effect is a hypothesis in the treatment of metastatic cancer whereby shrinkage of untreated tumors occur concurrently with shrinkage of tumors within the scope of the localized treatment.

Current Clinical
SFRT Problems:

  • The Peak Valley Dose Ratio is too low.
  • The radiation Beam is too broad/wide at 10-20mm, creating too much damage with a large radiation footprint.

NuVeta’s
Solution:

  • NuVeta will deliver beams 0.5mm thin.
  • This will allow NuVeta to fully harvest all the benefits of safe SFRT that would be consistent with the previous animal studies and repeat the same results in humans.

NuVeta’s system is also designed for priming.

Priming has far reaching implications:

  • Enhanced Tumor Uptake
  • Enhanced Immune Response

Watch the Video to Learn More:

Amazing potential for the unmet needs in cancer and non-cancerous diseases

  • Safely & effectively treat large, late stage, and treatment resistant cancers (clinical data exists)
  • Potentially, safely induce microvasculature regeneration in the extremities of diabetic and cancer patients to help resolve painful neuropathy (limited data so far)

Prototype system developed and tested in animal studies:

Prototype MRT system.
Window chamber based model study.

Contact Us:

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    Fractionated Radiotherapy

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    The Future of Cancer Treatment

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    Unmet Needs of Late Stage Patients

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    Our Solution

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    Best of All Worlds:

    The most Recent Developments in Therapy

    Want to learn more about NuVeta’s cutting edge Radation therapy?

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    Spatially Fractioned Radiation Therapy

    Spatially fractionated radiation therapy (SFRT) is a radiation therapy technique that allows for safe dose escalation for radiation treatment. Specialized beam collimation creates high-dose peaks organized throughout a target volume with intervening low-dose valleys.

    Flash Radiation Therapy

    FLASH radiotherapy (FLASH-RT) is a novel radiotherapy technology defined as a single ultra-high dose-rate (≥ 40 Gy/s) radiotherapy. Compared with conventional dose-rate irradiation, FLASH irradiation is 400-fold more rapid than conventional irradiation.

    Best of All Worlds:

    The most Recent Developments in Therapy

    Spatially Fractioned Radiation Therapy

    Spatially fractionated radiation therapy (SFRT) is a radiation therapy technique that allows for safe dose escalation for radiation treatment. Specialized beam collimation creates high-dose peaks organized throughout a target volume with intervening low-dose valleys.

    Flash Radiation Therapy

    FLASH radiotherapy (FLASH-RT) is a novel radiotherapy technology defined as a single ultra-high dose-rate (≥ 40 Gy/s) radiotherapy. Compared with conventional dose-rate irradiation, FLASH irradiation is 400-fold more rapid than conventional irradiation.

    Want to learn more about NuVeta’s cutting edge Radation therapy?

    Sign up below to get your patient or company access key and gain access to more information, data, and resources.

    SIGN UP

    Technology Rooted in Decades of Research

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